Volume 23, Spring 2013

Clinical Articles


Bilateral Hand Transplantation, a “Life-Saving” Operation?: A Case Report and Commentary
Tintle SM, Levin LS

Interfacility Transfer Utilization in the Management Pediatric Hand Injuries
Milby AH, Gunderson M, Gornitzky A, Chang B, Carrigan RB


The Genetic Nature of Osteochondritis Dissecans: A Systematic Review and Call for Improved Studies
Gans I, Ganley TJ

Operative Technique: Pediatric All-Epiphyseal Anterior Cruciate Ligament Reconstruction with Quadrupled Semitendinosus Autograft
Sarkissian EJ, Ganley TJ

Tibial Eminence Fractures: A Review and Algorithm for Treatment
Gans I, Ganley TJ


Four-Rod Constructs for Complex Spinopelvic Reconstruction
Milby AH, Slaughter JB, Smith HE, Arlet VM

C3-C4 Unilateral Facet Fracture Dislocation with Vertebral Artery Injury in an Adolescent: A Case Report, Review of the Literature, and Suggested Management Protocol
Kulkarni SS, O’Toole PO, Storm PB, Gunderson M, Wells L, Drummond DS

Review of Patient Reported Outcome Measures used in Pediatric Spinal Deformity Surgery
Harshavardhana NS, Dormans JP

Shoulder and Elbow

Do Diabetes and Hypertension Precede the Development of Adhesive Capsulitis?
Austin DC, Gans I, Park MJ, Carey JL, Kelly JD

Concurrent Ipsilateral Total Elbow Arthroplasty and Reverse Total Shoulder Arthroplasty: A Case Report and Review of the Literature
Horneff JG, Huffman GR

Arthroscopic Localization of the Coracohumeral Ligament
McHale KJ, Park MJ, Garcia G, Kelly JD

Sports Medicine

Operative Technique: Arthroscopic Remplissage
McHale KJ, Park MJ, Kelly JD

Pediatric ACL Injury Prevention: Improving Strength and Performance with a Prevention Program
Sarkissian EJ, Albaugh JD, Ganley TJ

Adult Reconstruction

Functional Recovery following Ceramic-on-Ceramic Total Hip Arthroplasty in Patients Younger than Fifty-Five Years of Age
Shah RP, Scolaro JA, Componovo R, Garino JP, Nelson CL, Lee GC

Long Tapered Hydroxyapatite-Coated Stems in Revision Total Hip Arthroplasty
Makani A, Kim TWB, Garino JP, Lee GC


The Cost of After-Hours Operative Debridement of Open Tibia Fractures
Schenker ML, Ahn J, Donegan DJ, Mehta S, Baldwin KD

Operative Technique: Scapula Fractures
Voleti PB, Namdari S, Mehta S

Blowing Smoke: A Meta-Analysis of the Effects of Smoking on Fracture Healing and Postoperative Infection
Schenker ML, Scolaro JA, Yannascoli SM, Baldwin KD, Mehta S, Ahn J


How to Write a Systematic Review: A Step-by-Step Guide
Yannascoli SM, Schenker ML, Carey JL, Ahn J, Baldwin KD

Practitioner Bias in the Interpretation of the Effects of Resident Work Hour Restrictions
Baldwin KD, Namdari S, Tjoumakaris F, Mehta S

Mentorship in Orthopaedics
Harshavardhana NS, Colo D, Dormans JP

Nanotechnology: Translational Applications in Orthopaedic Surgery
McHale KJ, Sullivan MP, Mehta S

Basic Science

Tendon Injury and Repair

Location-Specific Changes in Flexor Carpi Ulnaris Tendon Mechanical Properties in the Absence of Biglycan or Decorin
Buckley MR, Huffman GR, Iozzo RV, Birk DE, Soslowsky LJ

Effects of Decorin and Biglycan on Re-Alignment and Mechanical Properties of Aging Supraspinatus Tendons
Connizzo BK, Birk DE, Iozzo RV, Soslowsky LJ

Dynamic Mechanical Properties of Tendon Repair Tissue are Unaffected by Aging
Dunkman AA, Buckley MR, Mienaltowski MJ, Kumar A, Beason DP, Pathmanathan L, Birk DE, Soslowsky LJ

Injured Achilles Tendon Exhibits Inferior Mechanical and Structural Response During Fatigue Loading
Freedman BR, Sarver JJ, Voleti PB, Buckley MR, Soslowsky, LJ

Achilles Tendon Repair Response to Injury is Enhanced by the Absence of Decorin
Ilkhani-Pour S, Voleti PB, Buckley MR, Freedman BR, Iozzo R, Birk DE, Soslowsky LJ

Biceps Mechanical Properties Are Not Altered in the Presence of Asymptomatic Rotator Cuff Tendon Tears
Reuther KE, Thomas SJ, Satchell LN, Soslowsky LJ

Supraspinatus and Infraspinatus Rotator Cuff Repair Prevents Mechanical Damage to the Intact Subscapularis Tendon in a Rat Model
Reuther KE, Feeney E, Tucker JJ, Voleti PB, Glaser DL, Soslowsky LJ

Biceps Detachment Does Not Worsen Shoulder Function in a Multi-Tendon Rotator Cuff Tear Rat Model
Thomas SJ, Reuther KE, Sarver JJ, Tucker J, Satchell L, Glaser DL, Soslowsky LJ

Musculoskeletal Tissue Engineering

Hyaluronic Acid Hydrogels for Articular Cartilage Defect Repair in a Large Animal Model
Belkin NS, Fisher MB, Henning EA, Kim M, Bian L, Burdick JA, Steinberg DR, Mauck RL

Trajectory-based Tissue Engineering for Cartilage Repair: A Methodology to Better Predict In-Vivo Success
Fisher MB, Soegaard N, Henning EA, Dodge GR, Steinberg DR, Mauck RL

Mesenchymal Stem Cell-Based Cartilage is Unstable in Very Long Term In-Vitro Culture
Farrell MJ, Fisher MB, Soegaard N, Farrell KM, Mauck RL

An Inverse Agonist for Retinoic Acid Receptors Boosts Mesenchymal Stem Cell Chondrogenesis and Functional Properties of Tissue Engineered Cartilage
Farrell MJ, Chiaro JA, Henning EA, Pacifici M, Mauck RL

A High Throughput Mechanical Model to Study Injurious Compression of Engineered Cartilage
Mohanraj B, Hou C, Schmidt MM, Cosgrove BD, Mauck RL, Dodge GR

Depth-Dependent Properties of a Tri-layered Hyaluronic Acid Hydrogel Construct with Zonal Co-culture of Chondrocytes and MSCs
Kim M, Farrell MJ, Burdick JA, Mauck RL

Mesenchymal Stem Cells in Chondrogenic 3D Culture Are More Sensitive to Pro-Inflammatory Cytokines than Chondrocytes
Mohanraj B, Schmidt MM, Dodge GR, Mauck RL

Improved Meniscus Integration via Controlled Degradation of the Wound Interface
Qu F, Lin JG, Esterhai JL, Fisher MB, Mauck RL

Effects of Low Oxygen Tension on the Biomechanical Properties, Composition and mRNA Expression of Engineered Nucleus Pulposus
Gorth DJ, Chiaro JA, Dodge GR, Hebela NM, Elliott DM, Mauck RL, Smith LJ

Stem Cell Mechanobiology

Dynamic Stretch Rapidly Alters Nuclear Structure and Increases Chromatin Condensation in Mesenchymal Stem Cells
Heo S, Thorpe SD, Driscoll TP, Hashmi SK, Lee DA, Mauck RL

Cytoskeletal Tension is Required for Dynamic Tensile Loading Induced Alterations in Mesenchymal Stem Cell Shape and Nuclear Connectivity
Driscoll TP, Shurden ZE, Heo S, Mauck RL

Nanofiber Length Scale Differentially Impacts Meniscus and Mesenchymal Stem Cell Morphology and Nuclear Deformation
Silverstein AM, Heo S, Mauck RL

Fracture Healing

Disruption of Thrombospondin-2 Accelerates Ischemic Fracture Healing
Miedel EL, Dopkin D, Yu Y, Ahn J, Miclau T, Marcucio R, Hankenson K

A Mouse Model of Geriatric Fracture Healing: Toward the Elucidation of Aged Fracture Healing Deficiencies
Belkin NS, Lopas LA, Karp MR, Dopkin D, Dishowitz MI, Williams A, Mutyaba PL, Hankenson K, Ahn J

Bone Biology and Microarchitecture

A Closer Look at the Immediate Trabeculae Response to Combined Parathyroid Hormone and Alendronate Treatment
Altman A, Huh B, Luo S, Chandra A, Qin L, Liu X

3D Image Registration Is Critical to Ensure Accurate Detection of Longitudinal Changes in Bone Microstructure and Mineral Density Measurements in Rats by In Vivo Micro Computed Tomography
Luo S, Lan S, Chandra A, Huh B, Altman A, Qin L, Liu X

Fibrodysplasia Ossificans Progressiva

The FOP R206H Alk2 Mutation Enhances BMP-Induced Chondrogenic Differentiation
Culbert AC, Chakkalakal SA, Caron RJ, Shore EM

Functional Consequences of Fibrodysplasia Ossificans Progressiva-associated Mutations ACVR1R206H and ACVR1Q207E in Comparison to Constitutive Active ACVR1Q207D
Haupt J, Deichsel A, Stange K, Kajikhina E, Ast C, Souidi N, Kaplan FS, Shore EM, Seeman P